dc.contributor.author |
Çelebi, Bekir |
|
dc.contributor.author |
Özen, Mürüvvet Begüm |
|
dc.contributor.author |
Kip, Çiğdem |
|
dc.contributor.author |
Tuncel, Ali |
|
dc.date.accessioned |
2022-12-05T06:45:46Z |
|
dc.date.available |
2022-12-05T06:45:46Z |
|
dc.date.issued |
2014-09-03 |
|
dc.identifier.uri |
http://hdl.handle.net/20.500.11787/7782 |
|
dc.description.abstract |
Hydrophilic, polyacrylate-based, monosizedporous beads with zwitterionic molecular brushes were synthesized as a new stationary medium for hydrophilic interaction chromatography. Monosized-porous poly(glycerol1,3-diglycerolate diacrylate-co-glycerol dimethacrylate), poly(GDGDA-co-GDMA), beads 5 μm in size were obtained by a staged-shape template polymerization. As an initiator for surface-initiated atom transfer radical polymerization (SIATRP), bromine functionality was obtained on the beads by reacting their hydroxyl groups with 3-(aminopropyl)triethoxy silane and α-bromoisobutyryl bromide, respectively. Zwitterionic molecular brushes on the hydrophilic poly(GDGDA-coGDMA) beads were generated by SI-ATRP of a sulfobetaine monomer, [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl) ammonium hydroxide (MESH). Poly(MESH)-grafted poly(GDGDA-co-GDMA), poly(MESH)g-poly(GDGDAcoGDMA), beads were slurry packed into the microbore columns with 2 mm i.d. and evaluated as stationary medium for the separation of organic acids, nucleosides and peptides using microbore columns in hydrophilic interaction chromatography with the plate numbers up to 30,000 plates 1/m. |
tr_TR |
dc.language.iso |
eng |
tr_TR |
dc.rights |
info:eu-repo/semantics/openAccess |
tr_TR |
dc.subject |
Hydrophilic interaction chromatography |
tr_TR |
dc.subject |
HPLC |
tr_TR |
dc.subject |
Monodisperse porous particles |
tr_TR |
dc.subject |
Chromatographic packing |
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dc.subject |
Peptides |
tr_TR |
dc.subject |
Ethylene dimethacrylate |
tr_TR |
dc.title |
A new stationary phase for hydrophilic interaction chromatography: Polyacrylate‑based hydrophilic, monosized‑porous beads with zwitterionic molecular brushes |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.journal |
Chromatographia |
tr_TR |
dc.contributor.department |
Nevşehir Hacı Bektaş Veli Üniversitesi/fen-edebiyat fakültesi/kimya bölümü/fizikokimya anabilim dalı |
tr_TR |
dc.contributor.authorID |
332715 |
tr_TR |
dc.identifier.volume |
77 |
tr_TR |
dc.identifier.startpage |
1511 |
tr_TR |
dc.identifier.endpage |
1520 |
tr_TR |